Gene information
Official symbol MAPK10
Official full name mitogen-activated protein kinase 10
Gene type protein-coding gene
Chromosome4q21.3
Alias symbolJNK3; p493F12; p54bSAPK
Previous symbolPRKM10
Gene familyMitogen-activated protein kinases; MicroRNA protein coding host genes
Resources
Entrez Gene 5602
HGNC HGNC:6872
Ensembl ENSG00000109339
Vega OTTHUMG00000130604
UCSC uc003hpr.4
GO terms: 4 records
GO Description Category LogP Number of genes Detail
GO:0004672 protein kinase activity GO Molecular Functions -2.03527804 36 More
GO:0006468 protein phosphorylation GO Biological Processes -5.36604576 56 More
GO:0048511 rhythmic process GO Biological Processes -10.3377021 38 More
GO:0051090 regulation of DNA-binding transcription factor activity GO Biological Processes -25.8933515 78 More
KEGG pathways: 17 records
KEGG Description Category LogP Number of genes Detail
hsa04012 ErbB signaling pathway KEGG Pathway -2.03916116 5 More
hsa04014 Ras signaling pathway KEGG Pathway -9.01898803 33 More
hsa04024 cAMP signaling pathway KEGG Pathway -7.78464854 30 More
hsa04068 FoxO signaling pathway KEGG Pathway -6.87449445 21 More
hsa04140 Autophagy - animal KEGG Pathway -3.52554737 16 More
hsa04310 Wnt signaling pathway KEGG Pathway -2.72762629 16 More
hsa04380 Osteoclast differentiation KEGG Pathway -7.05199617 21 More
hsa04510 Focal adhesion KEGG Pathway -16.5268196 41 More
hsa04910 Insulin signaling pathway KEGG Pathway -1.75646958 6 More
hsa04917 Prolactin signaling pathway KEGG Pathway -3.17844000 10 More
hsa04920 Adipocytokine signaling pathway KEGG Pathway -10.4150431 19 More
hsa04930 Type II diabetes mellitus KEGG Pathway -3.96920305 9 More
hsa04931 Insulin resistance KEGG Pathway -8.40376708 21 More
hsa04935 Growth hormone synthesis, secretion and action KEGG Pathway -2.82078524 13 More
hsa05200 Pathways in cancer KEGG Pathway -30.6393212 92 More
hsa05210 Colorectal cancer KEGG Pathway -3.02613520 11 More
hsa05212 Pancreatic cancer KEGG Pathway -2.89550682 10 More
Drug-Gene interaction
view
Related drugs: 28 records
Drug name Interaction type Source PMID View
ast-487 DTC view
atorvastatin NCI 16701707 view
bentamapimod inhibitor ChemblInteractions view
brimapitide, c-terminal acid TdgClinicalTrial view
cc-401 inhibitor ChemblInteractions view
chembl35482 NCI 107539399467952 view
chembl406845 DTC view
doramapimod DTC view
dovitinib DTC view
epinephrine NCI 15210061 view
fibroblast growth factor-1 NCI 16682955 view
gefitinib DTC view
hesperadin inhibitor DTC 19035792 view
imatinib DTC view
insulin NCI 8766822 view
irinotecan NCI 16799812 view
isoproterenol NCI 12509508 view
jnj-7706621 DTC view
pf-00562271 DTC view
r-406 DTC view
sb-202190 DTC 22951114 view
sb-203580 DTC view
sirolimus NCI 15683719 view
sorafenib PharmGKB 20124951 view
sp-600125 DTC 23498914 view
tanzisertib inhibitor ChemblInteractions view
tozasertib DTC view
wortmannin NCI 15683719 view
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
cg18337337 hypermethylation epigenomics myocardial infarction[diagnosis] myocardial infarction Rask-Andersen M et al. Hum Mol Genet. 2016
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